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The patients with multiple malignancies are difficult to diagnose as one malignancy may be indolent and usually diagnosed as an incidental finding, while proceeding with staging work-up for the other malignancy. Treating such patients is even more difficult due to the issues related to sequencing the treatment for each of them. We report a case study where a patient was diagnosed with dual malignancies (Hodgkin’s lymphoma and adenocarcinoma lung) and was treated for both malignancies sequentially. The patient had five years of disease-free survival and was kept under follow-up. He was diagnosed with metachronous malignancy, squamous cell carcinoma of esophagus, and underwent treatment for the same condition.