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Upper extremity deep vein thrombosis can be occur according more different etiological reasons: presence of extraneous body, local infection, slow flow of blood, pressure of neck rib on big veins, etc. By searching a literature we found a presence of v.subclavian thrombosis in patients with permanent pacing system in significant values (apr. 40%), which is mostly clinically „dumb“, or asimptomatic. Permanent leed placed through v.subclaviae or v.chepalica represent extraneous body and in this conditions can occur malfunction of coagulation and vein thrombosis.