High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing

oleh: Peng Zhang, Ji-Han Xia, Jing Zhu, Ping Gao, Yi-Jun Tian, Meijun Du, Yong-Chen Guo, Sufyan Suleman, Qin Zhang, Manish Kohli, Lori S. Tillmans, Stephen N. Thibodeau, Amy J. French, James R. Cerhan, Li-Dong Wang, Gong-Hong Wei, Liang Wang

Format: Article
Diterbitkan: Nature Portfolio 2018-05-01

Deskripsi

Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of functional SNPs at disease risk loci.