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High-throughput screening of prostate cancer risk loci by single nucleotide polymorphisms sequencing
oleh: Peng Zhang, Ji-Han Xia, Jing Zhu, Ping Gao, Yi-Jun Tian, Meijun Du, Yong-Chen Guo, Sufyan Suleman, Qin Zhang, Manish Kohli, Lori S. Tillmans, Stephen N. Thibodeau, Amy J. French, James R. Cerhan, Li-Dong Wang, Gong-Hong Wei, Liang Wang
Format: | Article |
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Diterbitkan: | Nature Portfolio 2018-05-01 |
Deskripsi
Functional characterization of disease-causing variants at risk loci in cancer is challenging. Here, in prostate cancer the authors report a pipeline for high-throughput single-nucleotide polymorphisms sequencing (SNPs-seq) for large scale screening of functional SNPs at disease risk loci.