A shape-shifting redox foldase contributes to Proteus mirabilis copper resistance
oleh: Emily J. Furlong, Alvin W. Lo, Fabian Kurth, Lakshmanane Premkumar, Makrina Totsika, Maud E. S. Achard, Maria A. Halili, Begoña Heras, Andrew E. Whitten, Hassanul G. Choudhury, Mark A. Schembri, Jennifer L. Martin
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-07-01 |
Deskripsi
Bacterial disulfide isomerases shuffle incorrect disulfide bonds. Here, the authors structurally characterize the disulfide isomerase ScsC fromProteus mirabilisand identify a functionally important shape-shifting motif that allows ScsC to adopt a diverse range of conformations and enable swarming in the presence of copper stress.