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Takotsubo syndrome is a rare entity, and the occurrence of Bartter syndrome along with Takotsubo syndrome makes it a bizarre incidence. Diagnosis of both is very crucial and important, as the signs and symptoms tend to be different for each patient. Here, the authors present a case of Takotsubo cardiomyopathy with acquired Bartter-like phenotype and colonic stricture. It was promptly diagnosed and well managed at first incidence, but failing a timely follow-up led to mortality of patient, which highlights the importance of follow-up.