Insights into the GSDMB-mediated cellular lysis and its targeting by IpaH7.8
oleh: Hang Yin, Jian Zheng, Qiuqiu He, Xuan Zhang, Xuzichao Li, Yongjian Ma, Xiao Liang, Jiaqi Gao, Benjamin L. Kocsis, Zhuang Li, Xiang Liu, Neal M. Alto, Long Li, Heng Zhang
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-01-01 |
Deskripsi
The multifunctional GSDMB protein is an important molecule in human immunity. Here, the authors decipher the molecular mechanisms of GSDMB targeting by the bacterial virulence factor IpaH7.8 and provide insights into GSDMB-mediated pyroptosis.