Mechanism of Drug-Eluting Stent Thrombosis Diagnosed by Histopathological Evaluation of Directional Coronary Atherectomy Specimen

oleh: Kazuki Ito, MD, Shinya Fujita, MD, Atsushi Sakamoto, MD, PhD, Hayato Ohtani, MD, PhD, Masahiro Muto, MD, Yuichiro Maekawa, MD, PhD

Format: Article
Diterbitkan: Elsevier 2023-12-01

Deskripsi

An 89-year-old man with a history of percutaneous coronary intervention using a sirolimus-eluting stent presented with recurrent in-stent occlusion. Pathological assessment of the neointima resected via directional coronary atherectomy revealed a double-layered thrombus. Clopidogrel resistance and limited antithrombotic regimen owing to high bleeding risk likely resulted in the in-stent thrombotic occlusion.