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Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response
oleh: Xiang Yu, Yanfeng Dai, Yifan Zhao, Shuhong Qi, Lei Liu, Lisen Lu, Qingming Luo, Zhihong Zhang
Format: | Article |
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Diterbitkan: | Nature Portfolio 2020-02-01 |
Deskripsi
The bee venom melittin has anti-tumor properties but is unsuitable for therapeutic use on its own. Here, the authors generate melittin-nanoparticles and demonstrate that the nanoparticles reduce tumor growth and generate an anti-tumor immune response.