Melittin-lipid nanoparticles target to lymph nodes and elicit a systemic anti-tumor immune response

oleh: Xiang Yu, Yanfeng Dai, Yifan Zhao, Shuhong Qi, Lei Liu, Lisen Lu, Qingming Luo, Zhihong Zhang

Format: Article
Diterbitkan: Nature Portfolio 2020-02-01

Deskripsi

The bee venom melittin has anti-tumor properties but is unsuitable for therapeutic use on its own. Here, the authors generate melittin-nanoparticles and demonstrate that the nanoparticles reduce tumor growth and generate an anti-tumor immune response.