Evolutionary route of nasopharyngeal carcinoma metastasis and its clinical significance
oleh: Mei Lin, Xiao-Long Zhang, Rui You, You-Ping Liu, Hong-Min Cai, Li-Zhi Liu, Xue-Fei Liu, Xiong Zou, Yu-Long Xie, Ru-Hai Zou, Yi-Nuan Zhang, Rui Sun, Wei-Yi Feng, Hai-Yan Wang, Gui-Hua Tao, Hao-Jiang Li, Wen-Jie Huang, Chao Zhang, Pei-Yu Huang, Jin Wang, Qi Zhao, Qi Yang, Hong-Wan Zhang, Ting Liu, Hui-Feng Li, Xiao-Bing Jiang, Jun Tang, Yang-Kui Gu, Tao Yu, Zhi-Qiang Wang, Lin Feng, Tie-Bang Kang, Zhi-Xiang Zuo, Ming-Yuan Chen
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-02-01 |
Deskripsi
It is critical to understand the factors that are associated with nasopharyngeal carcinoma (NPC) progression, metastasis and response to therapy. Here, the authors analyse primary and metastatic NPC samples using bulk and single-cell sequencing, and find two distinct evolutionary routes that lead to metastasis.