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Introduction: Tuberculosis differs clinically and radiologically in the geriatrics compared with young. Objective: The objective of the following study is to compare the profile and treatment outcome of geriatric and young tuberculosis patients. Materials and Methods: A retrospective analysis of 58 tuberculosis patients seen from November 2010 to December 2011. Study period was October to December 2012 in tuberculosis unit of Burdwan district of West Bengal Data were analyzed using Statistical Package for the Social Sciences  software (version 19.0 Inc., IBM, Chicago, IL, USA). Results: Male populations were significantly more among geriatric patients. New smear positive sputum conversion and relapse cases were found more in the geriatric age group Overall, unfavorable outcome was significantly higher in geriatric compared with younger age population (33.3% vs. 17.8%). Conclusion: Geriatric and pediatric tuberculosis patients differ in diseases characteristics and outcome.