Neat synthesis and antioxidant activity of α-aminophosphonates
oleh: Guna Subba Reddy, Kunda Uma Maheswara Rao, Chereddy Syama Sundar, Sarva Santhi Sudha, Buchammagari Haritha, Sirasanagandla Swapna, Cirandur Suresh Reddy
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2014-11-01 |
Deskripsi
A simple, efficient, and environmentally benign method for a three-component reaction of an amine, an aldehyde and diethyl phosphite catalyzed by Amberlyst-15 has been developed to afford α-amino phosphonates in high yields and short reaction times under solvent-free reaction conditions using microwave irradiation. The major advantages of the present method are inexpensive, ecofriendly and reusable catalyst and also studied their antioxidant activity of synthesized compounds.