Non-CG methylation and multiple histone profiles associate child abuse with immune and small GTPase dysregulation
oleh: Pierre-Eric Lutz, Marc-Aurèle Chay, Alain Pacis, Gary G. Chen, Zahia Aouabed, Elisabetta Maffioletti, Jean-François Théroux, Jean-Christophe Grenier, Jennie Yang, Maria Aguirre, Carl Ernst, Adriana Redensek, Léon C. van Kempen, Ipek Yalcin, Tony Kwan, Naguib Mechawar, Tomi Pastinen, Gustavo Turecki
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-02-01 |
Deskripsi
Early-life adversity is thought to increase the risk of psychopathology through epigenetic mechanisms. Here, the authors profile 6 histone marks, chromatin states and DNA methylation in the lateral amygdala in subjects with a history of early-life adversity.