Ecological niche adaptation of Salmonella Typhimurium U288 is associated with altered pathogenicity and reduced zoonotic potential
oleh: Mark Kirkwood, Prerna Vohra, Matt Bawn, Gaëtan Thilliez, Hannah Pye, Jennifer Tanner, Cosmin Chintoan-Uta, Priscilla Branchu, Liljana Petrovska, Timothy Dallman, Neil Hall, Mark P. Stevens, Robert A. Kingsley
| Format: | Article |
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| Diterbitkan: | Nature Portfolio 2021-04-01 |
Deskripsi
Mark Kirkwood et al. take an epidemiological, genomic, phylogenetic, and experimental approach to assess the evolutionary origins and virulence of the U288 and ST34 isolates of Salmonella enterica in affecting livestock and potentially humans. Their results indicate that the molecular evolution of these isolates is associated with altered pathogenicity in pigs and reduced zoonotic potential of U288.