Emergence of SARS-COV-2 Spike Protein Escape Mutation Q493R after Treatment for COVID-19

oleh: Daniele Focosi, Federica Novazzi, Angelo Genoni, Francesco Dentali, Daniela Dalla Gasperina, Andreina Baj, Fabrizio Maggi

Format: Article
Diterbitkan: Centers for Disease Control and Prevention 2021-10-01

Deskripsi

We report in vivo selection of a severe acute respiratory syndrome coronavirus 2 spike mutation (Q493R) conferring simultaneous resistance to bamlanivimab and etesivimab. This mutation was isolated from a patient who had coronavirus disease and was treated with these drugs.