The calcium sensor Copine-6 regulates spine structural plasticity and learning and memory
oleh: Judith R. Reinhard, Alexander Kriz, Milos Galic, Nico Angliker, Mathieu Rajalu, Kaspar E. Vogt, Markus A. Ruegg
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2016-05-01 |
Deskripsi
Learning and memory depend on the structural and functional plasticity of synapses. Reinhard et al. show that the calcium sensor Copine-6 is required for memory, controls spine structure by regulating Rac signalling, and through its modulation of actin, supports hippocampal LTP.