Ultra-long-acting tunable biodegradable and removable controlled release implants for drug delivery
oleh: S. Rahima Benhabbour, Martina Kovarova, Clinton Jones, Daijha J. Copeland, Roopali Shrivastava, Michael D. Swanson, Craig Sykes, Phong T. Ho, Mackenzie L. Cottrell, Anush Sridharan, Samantha M. Fix, Orrin Thayer, Julie M. Long, Daria J. Hazuda, Paul A. Dayton, Russell J. Mumper, Angela D. M. Kashuba, J. Victor Garcia
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2019-09-01 |
Deskripsi
Patient drug regime compliance is a major issue; sustained release implants could address this. Here, the authors report on a phase inverted in situ forming implant of PLGA for the sustained release of antiretroviral drugs and optimize and demonstrate the release of 6 different drugs over a period of up to a year.