Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country
oleh: Lishuang Shen, Jennifer Dien Bard, Jennifer Dien Bard, Jaclyn A. Biegel, Jaclyn A. Biegel, Alexander R. Judkins, Alexander R. Judkins, Xiaowu Gai, Xiaowu Gai
| Format: | Article |
|---|---|
| Diterbitkan: | Frontiers Media S.A. 2020-09-01 |
Deskripsi
Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the city-, state-, and country-levels, and temporal transmissions. This points to the effectiveness of existing travel restriction policies and public health measures in reducing the transmission of SARS-CoV-2.