Consistent tumorigenesis with self-assembled hydrogels enables high-powered murine cancer studies
oleh: Abigail K. Grosskopf, Santiago Correa, Julie Baillet, Caitlin L. Maikawa, Emily C. Gale, Ryanne A. Brown, Eric A. Appel
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-08-01 |
Deskripsi
Grosskopf et al. report the development of a tumor inoculation method using self-assembled alginate hydrogels containing different tumorigenic molecules to reproducibly generate tumors in a subcutaneous murine tumor model. They show the impact of this improved model on the reduction of cohort size and increase in the power of the study design.