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In vitro evaluation of cytotoxicity and oxidative damage induced by ochratoxin A and aflatoxin B1: protective role of antioxidants
oleh: F. Cheli, B. Bertasi, E. Pavoni, R. Rebucci, N. Losio, L. Sangalli, E. Fusi, A. Baldi
| Format: | Article |
|---|---|
| Diterbitkan: | Taylor & Francis Group 2011-03-01 |
Deskripsi
In animal nutrition, mycotoxins are important feed contaminants. Among them, ochratoxins (OTA) and aflatoxins (AF) have several biological activities, including acute toxicity, teratogenicity, mutagenicity, immunotoxicity and carcinogenicity (Creepy, 2002). Obviously, toxicity of mycotoxins is a risk factor not only for animals but for humans, too (Hussein et al., 2001). Deficiencies of certain nutritional factors e.g. micronutrients may predispose or enhance individuals to the toxic effects of mycotoxins (Atroshi et al., 2002). It is well known that antioxidants like vitamin E, protect cellular membranes from oxidative damage.........