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Chromatin remodeller Fun30Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation
oleh: Junwoo Lee, Eun Shik Choi, Hogyu David Seo, Keunsoo Kang, Joshua M. Gilmore, Laurence Florens, Michael P. Washburn, Joonho Choe, Jerry L. Workman, Daeyoup Lee
Format: | Article |
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Diterbitkan: | Nature Portfolio 2017-02-01 |
Deskripsi
Nucleosomes have been shown to impede the elongation of RNA polymerase II during transcription. Here, the authors provide evidence that in fission yeast chromatin remodeller Fun30Fft3 localizes to transcribing regions to promote transcription by nucleosome disassembly in vivo.