Hypoxia-induced inhibin promotes tumor growth and vascular permeability in ovarian cancers
oleh: Ben Horst, Shrikant Pradhan, Roohi Chaudhary, Eduardo Listik, Liz Quintero-Macias, Alex Seok Choi, Michael Southard, Yingmiao Liu, Regina Whitaker, Nadine Hempel, Andrew Berchuck, Andrew B. Nixon, Nam Y. Lee, Yoav I. Henis, Karthikeyan Mythreye
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-06-01 |
Deskripsi
Hypoxia increases levels of the heteromeric TGFβ ligand inhibin in ovarian cancer and inhibin promotes tumor growth, endothelial cell invasion and permeability.