Down syndrome associated moyamoya may worsen epilepsy control and can benefit from surgical revascularization
oleh: Sarah R. Garson, Stephen J. Monteith, Sheila D. Smith, Bart P. Keogh, Ryder P. Gwinn, Michael J. Doherty
| Format: | Article |
|---|---|
| Diterbitkan: | Elsevier 2019-01-01 |
Deskripsi
Objectives: To examine outcome of bilateral extracranial to intracranial (EC-IC) bypass surgeries for a Down syndrome patient with hard-to-treat epilepsy and moyamoya. Materials and methods: Superficial temporal arteries were anastamosed using an indirect bypass technique to middle cerebral arteries bilaterally to help limit perfusion deficits and seizure controls. Results: Two superficial temporal to middle cerebral artery indirect bypass surgeries were performed within 3 months. Post-revascularization improvements included seizure control, gait, perfusion, wakefulness, language and quality of life. Conclusion: In patients with Down syndrome and moyamoya, improvements in seizure control and quality of life may occur with EC-IC bypass procedures. Keywords: Bypass, Perfusion, Stenosis