GhostKnockoff inference empowers identification of putative causal variants in genome-wide association studies
oleh: Zihuai He, Linxi Liu, Michael E. Belloy, Yann Le Guen, Aaron Sossin, Xiaoxia Liu, Xinran Qi, Shiyang Ma, Prashnna K. Gyawali, Tony Wyss-Coray, Hua Tang, Chiara Sabatti, Emmanuel Candès, Michael D. Greicius, Iuliana Ionita-Laza
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
The authors present GhostKnockoff, a method for genome-wide association studies which can be applied to enhance existing and future studies to identify functional variants with weaker statistical effects that might be missed by conventional association tests.