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Cobalt-catalyzed enantioselective intramolecular reductive cyclization via electrochemistry
oleh: Shiquan Gao, Chen Wang, Junfeng Yang, Junliang Zhang
Format: | Article |
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Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
1,6 enynes are a useful synthetic building block, but their use asymmetric intramolecular reductive couplings with cobalt catalysts have not been well-explored. Here, the authors describe an enantioselective intramolecular reductive coupling of enynes via the combination of electrochemistry and cobalt catalysis.