Cobalt-catalyzed enantioselective intramolecular reductive cyclization via electrochemistry

oleh: Shiquan Gao, Chen Wang, Junfeng Yang, Junliang Zhang

Format: Article
Diterbitkan: Nature Portfolio 2023-03-01

Deskripsi

1,6 enynes are a useful synthetic building block, but their use asymmetric intramolecular reductive couplings with cobalt catalysts have not been well-explored. Here, the authors describe an enantioselective intramolecular reductive coupling of enynes via the combination of electrochemistry and cobalt catalysis.