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Shared genetic risk factors and causal association between psoriasis and coronary artery disease
oleh: Matthew T. Patrick, Qinmengge Li, Rachael Wasikowski, Nehal Mehta, Johann E. Gudjonsson, James T. Elder, Xiang Zhou, Lam C. Tsoi
Format: | Article |
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Diterbitkan: | Nature Portfolio 2022-11-01 |
Deskripsi
Coronary artery disease (CAD) and psoriasis are established comorbidities, however their molecular relationship remains unclear. Here, the authors performed trans-disease meta-analysis, highlighting four genetic loci with evidence of colocalization, and prioritized genes based on multiomic data integration.