Methyl (3S,10b'S)-5-chloro-9′-fluoro-1-methyl-2-oxo-5′-phenyl-10b'H-spiro[indoline-3,1′-pyrazolo[3,2-a]isoquinoline]-2′-carboxylate

oleh: Piskala Subburaman Kannan, PanneerSelvam Yuvaraj, Boreddy Siva Rami Reddy, Rajamani Raja, Arunachalathevar SubbiahPandi

Format: Article
Diterbitkan: International Union of Crystallography 2013-06-01

Deskripsi

In the title compound, C27H19ClFN3O3, the pyrazole ring has a twist conformation and the six-membered ring to which it is fused has a screw-boat conformation. The mean plane of the pyrazole ring is inclined to the 2-methylindoline ring by 85.03 (9) and by 28.17 (8)° to the mean plane of the isoquinoline ring system. In the crystal, molecules are linked by pairs of C—H...F hydrogen bonds, forming inversion dimers. These dimers are linked via C—H...O hydrogen bonds, forming a two-dimensional network lying parallel to (10-1).