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Objectives: To examine the impact of glycaemic homeostasis on arterial stiffness and cardiac diastolic function in healthy subjects. Methods: Subjects (100 male & 115 female) were normotensive and normolipidaemic and had normal oral glucose tolerance test responses. Carotid-femoral arterial stiffness (PWV) and atherosclerotic risk (carotid intima media thickness; CIMT) were measured. Early/late mitral valve filling velocity (MV E/A) and isovolumetric relaxation time (IVRT) was used to assess diastolic function. Glycosylated haemoglobin (HbA1c) was used to determine long-term glycaemic homeostasis. Anthropometrical measurements such as height, body mass and waist circumference were also measured. Results: Spearman’s correlation identified significant association between HbA1c and age (r=0.40, P<0.0001), waist height ratio (r=0.18, P<0.01), PWV (r=0.26, P<0.001), CIMT (r=0.18, P<0.05), MV E/A (r=−0.37, P<0.0001) and IVRT (r=0.28, P<0.01). In multiple regression analysis’s age remained the only independent predictor of PWV, CIMT, MV E/A and IVRT. Conclusion: Despite being clinically healthy, HbA1c is associated with greater arterial stiffness and poor diastolic function.