Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors
oleh: Daichao Wu, Alexander Kolesnikov, Rui Yin, Johnathan D. Guest, Ragul Gowthaman, Anton Shmelev, Yana Serdyuk, Dmitry V. Dianov, Grigory A. Efimov, Brian G. Pierce, Roy A. Mariuzza
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-01-01 |
Deskripsi
Structural immunology is critical in understanding the interplay between the immune response and the infective agent but such studies in T cells and SARS-CoV-2 lag behind those of antibodies and B-cell receptors. Here the authors assess recognition of SARS-CoV-2 spike epitopes and their natural variants by public and private T cell receptors.