Cryo-EM structure of the deltaretroviral intasome in complex with the PP2A regulatory subunit B56γ

oleh: Michał S. Barski, Jordan J. Minnell, Zuzana Hodakova, Valerie E. Pye, Andrea Nans, Peter Cherepanov, Goedele N. Maertens

Format: Article
Diterbitkan: Nature Portfolio 2020-10-01

Deskripsi

Human T-cell lymphotropic virus type 1 (HTLV-1) is a pathogenic deltaretrovirus. Here the authors resolve the cryo-EM structure of the deltaretroviral intasome in complex with the human host PP2A regulatory subunit.