Hallmarks of primate lentiviral immunodeficiency infection recapitulate loss of innate lymphoid cells

oleh: Joseph C. Mudd, Kathleen Busman-Sahay, Sarah R. DiNapoli, Stephen Lai, Virginia Sheik, Andrea Lisco, Claire Deleage, Brian Richardson, David J. Palesch, Mirko Paiardini, Mark Cameron, Irini Sereti, R. Keith Reeves, Jacob D. Estes, Jason M. Brenchley

Format: Article
Diterbitkan: Nature Portfolio 2018-09-01

Deskripsi

Innate lymphoid cells (ILCs) have been shown to be depleted during HIV-1 infection. Here the authors show that ILC loss is associated with CD4 depletion and gastrointestinal damage in a primate model of SIV infection.