Protein fibril length in cerebrospinal fluid is increased in Alzheimer’s disease
oleh: Peter Niraj Nirmalraj, Thomas Schneider, Lars Lüder, Ansgar Felbecker
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2023-03-01 |
Deskripsi
Liquid-based AFM on protein aggregates at single-fibril resolution from the cerebrospinal fluid of patients at various stages of AD reveals that mature fibrils from patients at advanced stage AD have longer length, distinct morphology and spatial organization.