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Effects of the extract obtained from the Dieffinbachia picta leaves were examined on the termite workers of Microcerotermes diversus using four treatments (T) including 25%, 50%, 75% and 100% by spraying. The results showed mortality rate in the termite workers at different periods of time. T100% recorded the highest mortality rates (8%, 8.67% and 9%) after 24, 48 and 72 hours respectively, while the minimum mortality in the insect workers was recorded at T25% as 1.7%, 2.3% and 3.7% after 24, 48 and 72 hours respectively. According to results of the present study, there is a possible advantage of the toxic properties of D. picta leaves as an alternative and effective plant pesticides for combating the termite of M. diversus.