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A functional family of fluorescent nucleotide analogues to investigate actin dynamics and energetics
oleh: Jessica Colombo, Adrien Antkowiak, Konstantin Kogan, Tommi Kotila, Jenna Elliott, Audrey Guillotin, Pekka Lappalainen, Alphée Michelot
Format: | Article |
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Diterbitkan: | Nature Portfolio 2021-01-01 |
Deskripsi
Actin polymerization provides force for vital processes of the eukaryotic cell, but our understanding of actin dynamics and energetics remains limited due to the lack of high-quality probes. Here authors identify a family of highly sensitive fluorescent nucleotide analogues which bind to actin and provide energy to power actin-based processes.