Characterizing DNA methylation signatures of retinoblastoma using aqueous humor liquid biopsy
oleh: Hong-Tao Li, Liya Xu, Daniel J. Weisenberger, Meng Li, Wanding Zhou, Chen-Ching Peng, Kevin Stachelek, David Cobrinik, Gangning Liang, Jesse L. Berry
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2022-09-01 |
Deskripsi
Retinoblastoma response to treatment is difficult to predict. Here, the authors show that DNA methylation of cfDNA from aqueous humour is altered in retinoblastoma patients and can be used to identify the molecular subtypes and potentially predict treatment response.