Antimicrobial peptide capsids of de novo design
oleh: Emiliana De Santis, Hasan Alkassem, Baptiste Lamarre, Nilofar Faruqui, Angelo Bella, James E. Noble, Nicola Micale, Santanu Ray, Jonathan R. Burns, Alexander R. Yon, Bart W. Hoogenboom, Maxim G. Ryadnov
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2017-12-01 |
Deskripsi
With the growing threat of antibiotic resistance, unconventional approaches to antimicrobial discovery are needed. Here, the authors present a peptide topology that mimics virus architecture and assembles into antimicrobial capsids that disrupt bacterial membranes upon contact.