Humoral and cellular responses after a third dose of SARS-CoV-2 BNT162b2 vaccine in patients with lymphoid malignancies

oleh: Daniel Re, Barbara Seitz-Polski, Vesna Brglez, Michel Carles, Daisy Graça, Sylvia Benzaken, Stéphane Liguori, Khaled Zahreddine, Margaux Delforge, Béatrice Bailly-Maitre, Benjamin Verrière, Emmanuel Chamorey, Jérôme Barrière

Format: Article
Diterbitkan: Nature Portfolio 2022-02-01

Deskripsi

Vaccination is effective in preventing severe COVID-19 symptoms. Here the authors monitor patients with hematopoietic malignancy to find the third dose of the mRNA vaccine, BNT162b2, only boosts the humoral immunity in those showing responses to 2nd dose vaccination but can induce an independent T-cell response in a fraction of seronegative patients.