Microfluidic active loading of single cells enables analysis of complex clinical specimens

oleh: Nicholas L. Calistri, Robert J. Kimmerling, Seth W. Malinowski, Mehdi Touat, Mark M. Stevens, Selim Olcum, Keith L. Ligon, Scott R. Manalis

Format: Article
Diterbitkan: Nature Portfolio 2018-11-01

Deskripsi

Single-cell detection methods are limited by the trade-off between flow rate and measurement precision. Here the authors introduce active loading, an optically triggered microfluidic system to concentrate diluted cell samples, which reduces clogging and decreases processing time in single-cell assays.