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Update on the Withdrawal from Long-term Use of Benzodiazepines in Patients with Chronic Insomnia Disorder
oleh: Jinxiang CHENG, Liping ZHANG, Changjun SU
Format: | Article |
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Diterbitkan: | Chinese General Practice Publishing House Co., Ltd 2022-09-01 |
Deskripsi
Benzodiazepines (BZDs) are indicated for the short-term treatment of chronic insomnia disorder, since real-world use of them in large doses for a long time could cause serious side effects. Patients with long-term use of BZDs are prone to BZDs tolerance and dependence, but sudden withdrawal from BZDs can lead to rebound and withdrawal symptoms, resulting in difficulty in withdrawal. We reviewed recent studies about the withdrawal from long-term use of BZDs in chronic insomnia disorder patients, focusing on the overview of BZDs, timing and strategy of withdrawal, and treatment of withdrawal symptoms. Our review will contribute to enriching the ideas of appropriately discontinuing BZDs in chronic insomnia disorder patients with long-term use of BZDs.