Unrelated cord blood transplant in children with high-risk acute lymphoblastic leukemia: a long-term follow-up

oleh: Anna Paola Iori, William Arcese, Filippo Milano, Elisabetta Calabrese, Giovanni Fernando Torelli, Walter Barberi, Maria Grazia Mascolo, Lidia De Felice, Maria Screnci, Barbarella Lucarelli, Luigi Malandruccolo, Maria Paola Perrone, Simona Salvatori, Luca Laurenti, Emilia Iannella, Roberto Ricci, Maria Luisa Moleti, Robin FoĆ 

Format: Article
Diterbitkan: Ferrata Storti Foundation 2007-08-01

Deskripsi

Background and Objectives The aim of this single center study was to assess the impact of pre-transplant factors on long-term follow-up in young patients affected by high-risk acute lymphoblastic leukemia (ALL) who underwent an unrelated cord blood transplant (CBT). The conditioning regimens, graft-versus-host disease (GVHD) prophylaxis and supportive policies were uniform for all patients.Design and Methods We analyzed the results of CBT performed in 30 patients, aged