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Case Report: Management of Recurrent Ovarian Squamous Cell Carcinoma With PD-1 Inhibitor
oleh: Xiao-chen Song, Yong-xue Wang, Mei Yu, Dong-yan Cao, Jia-xin Yang
Format: | Article |
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Diterbitkan: | Frontiers Media S.A. 2022-03-01 |
Deskripsi
Malignant transformations, such as ovarian squamous cell carcinoma (SCC) in ovarian mature cystic teratoma (OMCT), are rare tumors. The management of recurrent disease is still a challenge, and the gene mutations involved remain unclear. We herein report a recurrent case of ovarian SCC with a PIK3CA gene variation and immunohistochemical staining of programmed death-ligand 1 (PD-L1) >10%. This patient achieved clinical remission after platinum-based effective chemotherapy and programmed death 1 (PD-1) immunotherapy.