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We explore the potential of ultimate unification of the Standard Model matter and gauge sectors into a single <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>E</mi><mn>8</mn></msub></semantics></math></inline-formula> superfield in ten dimensions via an intermediate Pati–Salam gauge theory. Through a consistent realisation of a <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mrow><msup><mi mathvariant="double-struck">T</mi><mn>6</mn></msup><mo>/</mo><mrow><mo>(</mo><msub><mi mathvariant="double-struck">Z</mi><mn>6</mn></msub><mo>×</mo><msub><mi mathvariant="double-struck">Z</mi><mn>2</mn></msub><mo>×</mo><msub><mi mathvariant="double-struck">Z</mi><mn>2</mn></msub><mo>)</mo></mrow></mrow></semantics></math></inline-formula> orbifolding procedure and renormalisation group evolution of gauge couplings, we establish several novel benchmark scenarios for New Physics that are worth further phenomenological exploration.