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The goal of this study was to test the feasibility of time restricted eating (TRE) in adults with overweight and obesity. Participants (<i>n</i> = 50) logged all eating occasions (>0 kcal) for a 2-week run-in period using a smartphone application. Participants with eating duration ≥14 h enrolled in an open label, non-randomized, prospective 90-day TRE intervention, with a self-selected reduced eating window of 10 h. No dietary counseling was provided. Changes in anthropometrics, eating patterns and adherence after TRE were analyzed using <i>t</i>-tests or Wilcoxon Rank-Sum Test. The mean duration of the baseline eating window was 14 h 32 m ± 2 h 36 m (<i>n</i> = 50) with 56% of participants with duration ≥14 h. TRE participants (<i>n</i> = 16) successfully decreased their eating window from 16 h 04 m ± 1 h 24 m to 11 h 54 m ± 2 h 06 m (<i>p</i> < 0.001), and reduced the number of daily eating occasions by half (<i>p</i> < 0.001). Adherence to logging and to the reduced eating window was 64% ± 22% and 47% ± 19%, respectively. TRE resulted in decreases in body weight (−2.1 ± 3.0 kg, <i>p</i> = 0.017), waist circumference (−2.2 ± 4.6 cm, <i>p</i> = 0.002) and systolic blood pressure (−12 ± 11 mmHg, <i>p</i> = 0.002). This study demonstrates the feasibility and efficacy of TRE administered via a smartphone, in adults with overweight and obesity.