The structural basis for RNA selectivity by the IMP family of RNA-binding proteins

oleh: Jeetayu Biswas, Vivek L. Patel, Varun Bhaskar, Jeffrey A. Chao, Robert H. Singer, Carolina Eliscovich

Format: Article
Diterbitkan: Nature Portfolio 2019-09-01

Deskripsi

ZBP1 and IMP2 belong to the IGF2BP family of RNA-binding proteins. Here the authors employed SELEX, NMR spectroscopy and mutagenesis to characterize the RNA-binding preference of ZBP1 and IMP2.