Expression of βE and γ-globin genes in infants heterozygous for hemoglobin E and double heterozygous for hemoglobin E and α-thalassemia
oleh: Pranee Winichagoon, Saovaros Svasti, Pattanee Winichagoon, Chureeporn Chitchumroonchokchai, Suthat Fucharoen
| Format: | Article |
|---|---|
| Diterbitkan: | Ferrata Storti Foundation 2007-05-01 |
Deskripsi
This study described the expression of βE-globin in newborns heterozygous for HbE. Despite the lower level of HbE, the pattern of βE-globin gene expression was similar to βA-globin because the increase in HbE and HbA reached the peak level at the same time. A delayed decline of HbF was observed.