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Anemia in female patients with solid neoplasms is corrected to normalize hemoglobin levels, to increase quality of life, and to improve antitumor therapy tolerance. The clinical application of recombinant human erythropoietin preparations has become an important treat- ment step that permits multiple hemotransfusions to be avoided. Epostim is effective and safe in increasing hemoglobin and packed cell volume and in overcoming the additive toxicity of chemo- and radiotherapy.