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Trauma is still the leading cause of death in children above one year of age even in countries with the most advanced medical services. Multiple trauma is always more than the sum of the single injuries; it should be considered as a systemic disease. Injury mechanisms vary with age. In infants non - accidental injuries (NAI) are common and are at higher risk for sustaining injury in the home environment. Fall is also major a cause of injury and home is the common place of injury. In caring for injured children the health care provider must be aware of the unique anatomic and physiological characteristics. This article is focused on these aspects only.