Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding

oleh: Liang Wang, Xin Wen, Zhengmao Wang, Zaisheng Lin, Chunhong Li, Huilin Zhou, Huimin Yu, Yuhan Li, Yifei Cheng, Yuling Chen, Geer Lou, Junmin Pan, Muqing Cao

Format: Article
Diterbitkan: Nature Portfolio 2022-07-01

Deskripsi

Cilia project from cells to serve sensory functions, and ciliary disruption can result in multiple disorders known as ciliopathies. Here the authors show that the ciliopathy gene TCTN1 functions to regulate the ciliary transition zone and ectosome formation.