Sex Disparities and Neutralizing-Antibody Durability to SARS-CoV-2 Infection in Convalescent Individuals
oleh: Alena J. Markmann, Natasa Giallourou, D. Ryan Bhowmik, Yixuan J. Hou, Aaron Lerner, David R. Martinez, Lakshmanane Premkumar, Heather Root, David van Duin, Sonia Napravnik, Stephen D. Graham, Quique Guerra, Rajendra Raut, Christos J. Petropoulos, Terri Wrin, Caleb Cornaby, John Schmitz, JoAnn Kuruc, Susan Weiss, Yara Park, Ralph Baric, Aravinda M. de Silva, David M. Margolis, Luther A. Bartelt
| Format: | Article |
|---|---|
| Diterbitkan: | American Society for Microbiology 2021-08-01 |
Deskripsi
In this study, we found that neutralizing antibody responses in COVID-19-convalescent individuals vary in magnitude but are durable and correlate well with receptor binding domain (RBD) Ig binding antibody levels compared to other SARS-CoV-2 antigen responses. In our cohort, higher neutralizing antibody titers are independently and significantly associated with male sex compared to female sex.