Optimized photochemistry enables efficient analysis of dynamic RNA structuromes and interactomes in genetic and infectious diseases
oleh: Minjie Zhang, Kongpan Li, Jianhui Bai, Willem A. Velema, Chengqing Yu, Ryan van Damme, Wilson H. Lee, Maia L. Corpuz, Jian-Fu Chen, Zhipeng Lu
| Format: | Article |
|---|---|
| Diterbitkan: | Nature Portfolio 2021-04-01 |
Deskripsi
RNA crosslinking and proximity ligation methods are used to identify transcriptome-wide base pairing interactions. Here, the authors report PARIS2 (psoralen analysis of RNA interactions and structures 2), a method for RNA duplex determination in vivo with higher efficiency than the previous PARIS method.