HIV-1 DNA sequence diversity and evolution during acute subtype C infection

oleh: Guinevere Q. Lee, Kavidha Reddy, Kevin B. Einkauf, Kamini Gounder, Joshua M. Chevalier, Krista L. Dong, Bruce D. Walker, Xu G. Yu, Thumbi Ndung’u, Mathias Lichterfeld

Format: Article
Diterbitkan: Nature Portfolio 2019-06-01

Deskripsi

The dynamics of HIV-1 DNA sequences early after HIV-1 transmission remains poorly characterized. Here, the authors perform a longitudinal evaluation of HIV-1 DNA sequences in subtype C-infected individuals during acute infection, providing a landscape of the nature and evolution of the very early viral genome.